During the Mozambique trial of a potential malaria vaccine, the effect of the drug was measured on:
Are the variables quantitative? Or categorical?
Without the drug, the rate of severe malaria infection in the area of the study was 34.9 children per 1000. Of 745 children given the drug, 11 got severe malaria during the course of the study. Does this data suggest that the drug reduces the rate of severe malaria infections?
Population? Sample? Statistic? Parameter?
“Efficacy of the RTS,S/AS202A vaccine against Plasmodium falciparum infection and disease in young African children: randomized controlled trial” by P. Alonso et al, The Lancet, Oct 16, 2004.
Note that 34.9/1000 = 0.0349 = 3.49%. This is the infection rate for the untreated population.
Let \( p \) be the proportion of treated children in the population who get sick if we treated all of them.